The ZyMōt Multi (850µL) Sperm Separation Device


In 5+ decades of reproductive medicine, technological innovations have changed the way patients achieve their dreams. Despite this progress, sperm preparation has not evolved: labs still centrifuge sperm. Until now.

The ZyMōt Multi (850µL) Sperm Separation Device prepares motile sperm from semen for use in intrauterine insemination (IUI) and intracytoplasmic sperm injection (ICSI) procedures. The device accepts 850µL of sample input and yields 500µL output volume for downstream use.

ZyMōt devices separate sperm based on motility, without the need for any centrifugation. Click here to learn more about how ZyMōt devices work

With about 5 minutes of total hands-on time per sample, every ZyMōt processed specimen represents a significant time savings over centrifugation-based methods. Simple to adopt and easy to use, ZyMōt devices improve training and standardization. No special media is required.

Fewer handling steps (a shorter chain of custody) translates into less risk for your lab, and more confidence for your patients. Learn more about how ZyMōt Sperm Separation Devices improve workflow and productivity.

The ZyMōt Multi (850µL) device can be used with the following sample types: “Normal”; Low count; Low motility (Note: Some motility is required); Viscous; Low volume; A combination of the above properties; Frozen samples.

Read more about the clinical performance of ZyMōt devices and see the publications featuring ZyMōt data.

Whether for ICSI or IUI use, there is no need for any centrifugation of the sample, either before or after device usage. Processing sperm with ZyMōt devices gives you more confidence and gives your patients more peace of mind.

Try it yourself and see the ZyMōt difference.

Comparison of microfluid sperm sorting chip and density gradient methods for use in intrauterine insemination cycles.
Gode, F., Bodur T., et al. Fertility and Sterility (2019). doi: 10.1016/j.fertnstert.2019.06.037

A treatment approach for couples with disrupted sperm DNA integrity and recurrent ART failure.
Parrella, A., Keating, D., Cheung, S. et al. J Assist Reprod Genet (2019). doi: 10.1007/s10815-019-01543-5

Selection of Functional Human Sperm with Higher DNA Integrity and Fewer Reactive Oxygen Species.
Asghar, W., Velasco, V., Kingsley, J. L. et al. Adv. Healthcare Mater. (2014), 3: 1671-1679. doi: 10.1002/adhm.201400058

To date, all studies and published clinical data regarding the use of ZyMōt Sperm Separation Devices have been focused on ICSI and IUI procedures. There have been no studies conducted, nor published data, on the use of ZyMōt devices for conventional insemination. ZyMōt Fertility is currently in the process of obtaining greater understanding and insight regarding the use of ZyMōt devices for conventional insemination. Consequently, we are requesting that clinicians limit their use of ZyMōt devices to ICSI and IUI cycles only. We look forward to assisting practices with successfully using our devices for their conventional insemination procedures and will provide updates as soon as they become available.

Video Demo:
The ZyMōt Multi (850µL)
Sperm Separation Device